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Structure of 10076-48-9
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Methyl 2,2-dimethoxypropanoate is a bench-stable, moisture-tolerant acetal ester featuring a geminal dimethoxy group that stabilizes adjacent carbonyl reactivity. This protected α-carbonyl synthon integrates readily into multistep synthesis, enabling controlled release of reactive intermediates under mild acidic conditions.
Methyl 2,2-dimethoxypropanoate serves as a stable, bench-ready acylating agent that facilitates efficient formation of ketones via nucleophilic addition followed by hydrolysis. Its dimethoxyacetyl moiety enables reliable carbon–carbon bond construction in multistep syntheses, particularly in the preparation of α-hydroxy and α-amino carbonyl derivatives. The compound exhibits excellent functional group tolerance and simplifies purification due to its crystalline nature and predictable reaction profile.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: