Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Maleimide-DOTA

  • CAS No. 1006711-90-5

  • Cat. No. CS-0127560
  • Molecule weight526.54
  • Purity≥97%
  • MDL No.MFCD32708535

*For research and further manufacturing use only, not for direct human use.

Maleimide-DOTA|CS-0127560

Structure of 1006711-90-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1006711-90-5
  • Cat. No. CS-0127560
  • Purity ≥97%
  • MDL No. MFCD32708535
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₃₄N₆O₉
  • Molecular Weight 526.54
  • Synonym(s) Maleimido-mono-amide-DOTA
  • SMILES O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(NCCN2C(C=CC2=O)=O)=O)CC1

Description

Maleimide-DOTA features a maleimide group conjugated to a DOTA chelator, enabling site-specific bioconjugation via thiol-reactive addition. This bifunctional linker combines the robust metal-binding capacity of DOTA with efficient coupling to cysteine residues, facilitating the creation of stable radiolabeled probes for targeted imaging and theranostic applications under physiological conditions.

Application

Maleimide-DOTA serves as a versatile bifunctional chelator enabling site-specific conjugation to thiol-containing biomolecules via Michael addition, while providing robust metal coordination for radiometals such as Gd³⁺ and Lu³⁺. Its high stability and aqueous compatibility make it ideal for constructing targeted imaging agents and therapeutic conjugates in preclinical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   191.34
  • LogP   -3.497
  • H_Acceptors   10
  • H_Donors   4
  • Rotatable_Bonds   11

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Maleimide-DOTA sigmaMaleimide-DOTA manufacturerMaleimide-DOTA priceMaleimide-DOTA structureMaleimide-DOTA SDSbuy Maleimide-DOTAMaleimide-DOTA supplierMaleimide-DOTA usesMaleimide-DOTA molecular weightprice of Maleimide-DOTAMaleimide-DOTA chemical name formula of Maleimide-DOTA
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label