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CS-W001157 4
Total: USD 88.00

2-Aminopyrimidin-4-ol

  • CAS No. 100643-25-2

  • Cat. No. CS-0166939
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Aminopyrimidin-4-ol|CS-0166939

Structure of 100643-25-2

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General Information

  • CAS No. 100643-25-2
  • Cat. No. CS-0166939
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅N₃O
  • Molecular Weight 111.10
  • Synonym(s) 4-Pyrimidinol, 2-amino- (9CI)
  • SMILES OC1=NC(N)=NC=C1

Description

2-Aminopyrimidin-4-ol features a fused heterocyclic scaffold with complementary amine and hydroxyl groups, enabling versatile coordination in metal-ligand systems. This bench-stable compound integrates readily into pharmaceutical intermediates and functional materials, offering enhanced solubility and reactivity under standard conditions.

Application

2-Aminopyrimidin-4-ol serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds prevalent in kinase inhibitors and antiviral agents. Its dual functionality—amine and phenolic hydroxyl—facilitates diverse downstream modifications, including Suzuki-Miyaura coupling, electrophilic substitution, and metal-catalyzed cross-coupling reactions. The compound exhibits good bench stability and is amenable to purification via recrystallization or column chromatography, making it well-suited for scalable synthesis and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H225
Precautionary Statements : P210-P243-P273-P403

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Computational Chemistry Data

  • TPSA   72.03
  • LogP   -0.2356
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   0

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