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Structure of 1005474-88-3
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5-Fluoro-6-methylpyridine-2-carboxylic acid features a strategically positioned fluorine atom and methyl group on the pyridine ring, enhancing electron deficiency and metabolic stability. This combination enables direct incorporation into bioactive scaffolds, particularly in kinase inhibitors and pharmaceutical intermediates. The carboxylic acid moiety provides a versatile handle for amide coupling and derivatization under standard conditions.
5-Fluoro-6-methylpyridine-2-carboxylic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard functional group transformations. Its orthogonal reactivity profile—combining a carboxylic acid for derivatization and strategically positioned fluorine and methyl groups—facilitates efficient late-stage modification in API development. The compound exhibits good bench stability and compatibility with common coupling reactions, supporting scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: