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CS-W001157 4
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2-Phenyl-2-(pyrrolidin-1-yl)acetic acid

  • CAS No. 100390-48-5

  • Cat. No. CS-0034117
  • Purity≥98%
  • MDL No.MFCD05237231

*For research and further manufacturing use only, not for direct human use.

2-Phenyl-2-(pyrrolidin-1-yl)acetic acid|CS-0034117

Structure of 100390-48-5

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General Information

  • CAS No. 100390-48-5
  • Cat. No. CS-0034117
  • Purity ≥98%
  • MDL No. MFCD05237231
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅NO₂
  • Molecular Weight 205.25
  • Synonym(s) Phenyl-pyrrolidin-1-yl-acetic acid
  • SMILES OC(C(N1CCCC1)C2=CC=CC=C2)=O

Description

2-Phenyl-2-(pyrrolidin-1-yl)acetic acid features a sterically hindered α-carbon bearing a pyrrolidine amine and a phenyl group, delivering enhanced solubility and stability in polar solvents. This scaffold integrates readily into bioactive molecule design, particularly in CNS-targeted compounds and kinase inhibitors.

Synthesis

  • Route1
    • null|null
      123-75-1
    • Glyoxalic acid 50%w/w in water|CS-W019807
      298-12-4
    • In-stock
      Phenylboronic acid|CS-W001090
      98-80-6
    • ~%
    • In-stock
      2-Phenyl-2-(pyrrolidin-1-yl)acetic acid|CS-0034117
      100390-48-5

    References

    • Tetrahedron Letters, , vol. 46, # 12 p. 2025 - 2028

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   1.9081
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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