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CS-W001157 4
Total: USD 88.00

(2,6-Dimethylphenyl)boronic acid

  • CAS No. 100379-00-8

  • Cat. No. CS-W002725
  • Purity≥97%
  • MDL No.MFCD01009693

*For research and further manufacturing use only, not for direct human use.

(2,6-Dimethylphenyl)boronic acid|CS-W002725

Structure of 100379-00-8

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General Information

  • CAS No. 100379-00-8
  • Cat. No. CS-W002725
  • Purity ≥97%
  • MDL No. MFCD01009693
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₂
  • Molecular Weight 149.98
  • Synonym(s) None
  • SMILES OB(c1c(C)cccc1C)O

Description

Reagent used forPalladium catalyzed Suzuki-Miyaura coupling reactions One-pot ipso-nitration of arylboronic acids including broader substrate scope of heterocycles and functional groups Nickel-Catalyzed Cross-Coupling of Chromene Acetals and Boronic Acids Visible-light initiated aerobic oxidative hydroxylation catalyzed by Ru-complex Rhodium(I)-catalyzed 1,4-addition reactions Pd-catalyzed homocouplings Expanded scope of Cu assisted Suzuki-Miyaura coupling reactions including aryl chlorides and polyhalo aryl boronates Reagent used in Prepration ofOrally bioavialable G Protein-Coupled Receptor 40 agonists for diabetes treatment Solid phase synthesis and antitumor structure-activity relationship of Smac triazoloprolines and biarylalanines tetrapeptide libraries Protein Kinase inhibitors

Synthesis

  • Route1
    • null|null
      121-43-7
    • In-stock
      2-Bromo-m-xylene|CS-W009028
      576-22-7
    • ~67%
    • In-stock
      (2,6-Dimethylphenyl)boronic acid|CS-W002725
      100379-00-8

    References

    • Tu, Tao; Sun, Zheming; Fang, Weiwei; Xu, Mizhi; Zhou, Yunfei Organic Letters, 2012 , vol. 14, # 16 p. 4250 - 4253
  • Route2
    • null|null
      121-43-7
    • null|null
      21450-64-6
    • ~%
    • In-stock
      (2,6-Dimethylphenyl)boronic acid|CS-W002725
      100379-00-8

    References

    • US6235740 B1, ; US 6235740 B1
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 3 p. 747 - 750

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.01676
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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