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CS-W001157 4
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5-(1-Hydroxyethyl)-2-methylpyridine

  • CAS No. 100189-16-0

  • Cat. No. CS-B0462
  • Molecule weight137.18
  • Purity≥98%
  • MDL No.MFCD06637422

*For research and further manufacturing use only, not for direct human use.

5-(1-Hydroxyethyl)-2-methylpyridine|CS-B0462

Structure of 100189-16-0

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General Information

  • CAS No. 100189-16-0
  • Cat. No. CS-B0462
  • Purity ≥98%
  • MDL No. MFCD06637422
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) 3-Pyridinemethanol,alpha,6-dimethyl-(6CI,9CI)
  • SMILES OC(C)C1=CC=C(C)N=C1

Description

5-(1-Hydroxyethyl)-2-methylpyridine features a pyridine core functionalized with a hydroxymethyl group at the 5-position and a methyl substituent at the 2-position. This configuration imparts enhanced solubility and reactivity, enabling efficient incorporation into ligand architectures and pharmaceutical intermediates. The pendant hydroxyl group supports further derivatization through oxidation or esterification, facilitating access to diverse molecular scaffolds.

Application

5-(1-Hydroxyethyl)-2-methylpyridine serves as a versatile building block in medicinal chemistry, enabling access to substituted pyridine scaffolds via standard functional group interconversions. The hydroxyl group facilitates derivatization through oxidation or substitution reactions, while the methyl and pyridine functionalities provide orthogonal reactivity for further elaboration. Its bench-stable nature and compatibility with common coupling protocols make it suitable for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.44332
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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