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CS-W001157 4
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1-(Pyridin-2-yl)propan-1-amine

  • CAS No. 100155-73-5

  • Cat. No. CS-0040139
  • Purity≥98%
  • MDL No.MFCD09802324

*For research and further manufacturing use only, not for direct human use.

1-(Pyridin-2-yl)propan-1-amine|CS-0040139

Structure of 100155-73-5

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General Information

  • CAS No. 100155-73-5
  • Cat. No. CS-0040139
  • Purity ≥98%
  • MDL No. MFCD09802324
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight 136.19
  • Synonym(s) 1-(2-Pyridyl)-1-propylamine
  • SMILES NC(CC)C1=NC=CC=C1

Description

1-(Pyridin-2-yl)propan-1-amine features a pyridine ring directly linked to a primary amine-bearing propyl chain, enabling strong coordination in catalytic systems. This nitrogen-rich scaffold offers enhanced solubility and stability in polar solvents, facilitating use in transition metal catalysis and ligand design.

Application

1-(Pyridin-2-yl)propan-1-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds through amine-directed functionalization. Its pyridyl group provides strong coordination for transition metals and enhances solubility in polar solvents, while the primary amine facilitates straightforward derivatization via alkylation, acylation, or reductive amination. The compound exhibits excellent bench stability and ease of purification, making it well-suited for multi-step synthesis and scale-up applications.

Synthesis

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    • In-stock
      1-(Pyridin-2-yl)propan-1-amine|CS-0040139
      100155-73-5

    References

    • Bower; Ramage Journal of the Chemical Society, 1955 , p. 2834,2836

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P233-P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P340-P362-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.4914
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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