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CS-W001157 4
Total: USD 88.00

Piperidine-4-carbothioamide

  • CAS No. 112401-09-9

  • Cat. No. CS-0149953
  • Purity≥95%
  • MDL No.MFCD09055273

*For research and further manufacturing use only, not for direct human use.

Piperidine-4-carbothioamide|CS-0149953

Structure of 112401-09-9

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General Information

  • CAS No. 112401-09-9
  • Cat. No. CS-0149953
  • Purity ≥95%
  • MDL No. MFCD09055273
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂N₂S
  • Molecular Weight 144.24
  • Synonym(s) PIPERDINE-4-CARBOTHIOAMIDE
  • SMILES NC(C1CCNCC1)=S

Description

Piperidine-4-carbothioamide features a thiocarbonyl group appended to the piperidine ring, delivering enhanced nucleophilicity and coordination versatility. This scaffold integrates readily into bioactive molecule design, offering favorable solubility and stability under standard bench conditions.

Application

Piperidine-4-carbothioamide serves as a versatile building block in medicinal chemistry, enabling the construction of thioamide-containing heterocycles and bioactive scaffolds. Its thiocarbonyl group exhibits moderate nucleophilicity and participates reliably in standard condensation reactions, facilitating the synthesis of diverse nitrogen- and sulfur-containing compounds. The molecule demonstrates good bench stability and compatibility with common protecting group strategies, supporting efficient downstream functionalization in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.2721
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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