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Structure of 100130-55-0
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2-Iodo-3-methylbenzaldehyde features a sterically accessible aldehyde group flanked by an iodine atom and a methyl substituent on the aromatic ring. This configuration enables direct functionalization in cross-coupling reactions, offering high reactivity under standard conditions while maintaining bench stability.
2-Iodo-3-methylbenzaldehyde serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The iodide group facilitates palladium-catalyzed coupling with boronic acids, esters, and other nucleophiles under standard conditions. The aldehyde functionality allows for subsequent transformations including reductive amination, Wittig reactions, and imine formation. Bench-stable and readily purified by column chromatography, it supports scalable synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: