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Fmoc-Gly-Gly-Gly-Gly

  • CAS No. 1001202-16-9

  • Cat. No. CS-0039300
  • Purity≥95%
  • MDL No.MFCD18427731

*For research and further manufacturing use only, not for direct human use.

Fmoc-Gly-Gly-Gly-Gly|CS-0039300

Structure of 1001202-16-9

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General Information

  • CAS No. 1001202-16-9
  • Cat. No. CS-0039300
  • Purity ≥95%
  • MDL No. MFCD18427731
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₄N₄O₇
  • Molecular Weight 468.46
  • Synonym(s) N-Fmoc-glycylglycylglycylglycine
  • SMILES O=C(O)CNC(CNC(CNC(CNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O)=O)=O

Description

Fmoc-Gly-Gly-Gly-Gly is a tetrapeptide building block featuring a C-terminal glycine residue and an N-terminal Fmoc protecting group. This sequence offers high solubility in common organic solvents and exhibits excellent stability under standard coupling conditions. The repetitive glycine motif enables efficient chain elongation in solid-phase peptide synthesis, minimizing steric hindrance during stepwise assembly.

Application

Fmoc-Gly-Gly-Gly-Gly serves as a linear tetrapeptide building block for solid-phase peptide synthesis, offering high stability and ease of purification. The Fmoc group enables efficient orthogonal deprotection under mild basic conditions, while the glycine sequence provides flexibility and minimal steric hindrance. This reagent facilitates rapid chain elongation in the synthesis of longer peptides and protein fragments, particularly useful in developing biologically active sequences requiring precise N-terminal control.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   162.93
  • LogP   -0.0417
  • H_Acceptors   6
  • H_Donors   5
  • Rotatable_Bonds   10

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