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(3-Fluorobenzyl)hydrazine dihydrochloride

  • CAS No. 1000805-94-6

  • Cat. No. CS-0053051
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3-Fluorobenzyl)hydrazine dihydrochloride|CS-0053051

Structure of 1000805-94-6

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General Information

  • CAS No. 1000805-94-6
  • Cat. No. CS-0053051
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁Cl₂FN₂
  • Molecular Weight 213.08
  • Synonym(s) 1-(3-FLUOROBENZYL)HYDRAZINE 2HCL
  • SMILES Cl.Cl.NNCC1=CC(F)=CC=C1

Description

(3-Fluorobenzyl)hydrazine dihydrochloride features a fluorinated aromatic scaffold that enhances metabolic stability and modulates electronic properties. The hydrazine moiety enables direct coupling in heterocycle synthesis, while the dihydrochloride salt form ensures improved solubility and handling under standard conditions.

Application

(3-Fluorobenzyl)hydrazine dihydrochloride serves as a versatile building block for the synthesis of hydrazone derivatives and heterocyclic scaffolds, particularly in medicinal chemistry and agrochemical research. Its bench-stable form facilitates handling and purification, while the ortho-fluoro substituent enables further functionalization via palladium-catalyzed cross-coupling or nucleophilic aromatic substitution. The hydrazine moiety reacts efficiently with aldehydes and ketones under mild conditions, enabling rapid access to bioactive hydrazone intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   1.6326
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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