Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

  • CAS No. 1000340-35-1

  • Cat. No. CS-W001275
  • Purity≥97%
  • MDL No.MFCD09880126

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde|CS-W001275

Structure of 1000340-35-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1000340-35-1
  • Cat. No. CS-W001275
  • Purity ≥97%
  • MDL No. MFCD09880126
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂O
  • Molecular Weight 225.04
  • Synonym(s) 4-BROMO-3-FORMYL-7-AZAINDOLE
  • SMILES O=CC1=CNC2=NC=CC(Br)=C21

Description

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde is a heterocyclic aldehyde featuring a brominated pyrrolopyridine core with a reactive formyl group at the 3-position. This scaffold integrates electron-deficient aromaticity and a handle for cross-coupling reactions, enabling efficient incorporation into bioactive molecules and advanced synthetic intermediates.

Application

4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyrrole and pyridine rings. The aldehyde group facilitates nucleophilic additions and condensation reactions, while the bromo substituent supports palladium-catalyzed cross-coupling transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing complex scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • 1H-Pyrrolo[2,3-b]pyridine-3-methanamine, 4-bromo-N,N-dimethyl-|CS-0004448
      1198277-82-5
    • null|null
      100-97-0
    • ~76%
    • In-stock
      4-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde|CS-W001275
      1000340-35-1

    References

    • WYETH LLC; AYRAL-KALOUSTIAN, Semiramis; MANSOUR, Tarek Suhayl; TSOU, Hwei-Ru; ZHANG, Nan; VENKATESAN, Aranapakam M.; DI, Li; KERNS, Edward H. Patent: WO2010/30727 A1, 2010 ; Location in patent: Page/Page column 120 ; WO 2010/030727 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   45.75
  • LogP   2.1379
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1000340-35-1 sigma1000340-35-1 manufacturer1000340-35-1 price1000340-35-1 structure1000340-35-1 SDSbuy 1000340-35-11000340-35-1 supplier1000340-35-1 uses1000340-35-1 molecular weightprice of 1000340-35-11000340-35-1 chemical name formula of 1000340-35-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label