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Structure of 1000164-43-1
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Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH features a rigid psi(Me,Me)pro conformational constraint that stabilizes beta-turn structures in peptide synthesis. The Fmoc group enables efficient solid-phase coupling, while the tBu-protected serine side chain ensures compatibility with standard deprotection protocols. This dipeptide building block facilitates the construction of biologically active sequences requiring precise backbone geometry.
Fmoc-Ser(tBu)-Ser(ψ(Me,Me)Pro)-OH serves as a versatile dipeptide building block for the synthesis of peptide macrocycles and constrained peptides. The psi(Me,Me)Pro motif enforces a rigid turn conformation, enhancing structural stability and bioavailability. The Fmoc group enables efficient stepwise solid-phase peptide synthesis, while the tBu protecting group on the serine side chain ensures orthogonal deprotection. This scaffold facilitates reliable incorporation into cyclic peptides and peptidomimetics with defined secondary structures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: