Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,6-Dibromo-4-(trifluoromethyl)pyridine

  • CAS No. 1000152-84-0

  • Cat. No. CS-0041083
  • Purity≥98%
  • MDL No.MFCD22682722

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromo-4-(trifluoromethyl)pyridine|CS-0041083

Structure of 1000152-84-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1000152-84-0
  • Cat. No. CS-0041083
  • Purity ≥98%
  • MDL No. MFCD22682722
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Br₂F₃N
  • Molecular Weight 304.89
  • Synonym(s) None
  • SMILES FC(C1=CC(Br)=NC(Br)=C1)(F)F

Description

2,6-Dibromo-4-(trifluoromethyl)pyridine features a pyridine core bearing two bromine substituents at the 2 and 6 positions and a strongly electron-withdrawing trifluoromethyl group at the 4 position. This combination imparts high electrophilicity and stability under standard bench conditions, enabling efficient coupling reactions in cross-coupling and heterocyclic synthesis. The molecule’s steric and electronic profile facilitates selective functionalization in complex molecular architectures.

Application

2,6-Dibromo-4-(trifluoromethyl)pyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity at the 2- and 6-bromo positions. The trifluoromethyl group enhances metabolic stability and modulates electronic properties, making it valuable for constructing bioactive scaffolds. Its bench-stable crystalline form facilitates handling and purification, supporting scalable applications in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • ISHIHARA SANGYO KAISHA, LTD. Patent: EP2030971 A1, 2009 ; Location in patent: Page/Page column 20 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.6254
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,6-Dibromo-4-(trifluoromethyl)pyridine sigma2,6-Dibromo-4-(trifluoromethyl)pyridine manufacturer2,6-Dibromo-4-(trifluoromethyl)pyridine price2,6-Dibromo-4-(trifluoromethyl)pyridine structure2,6-Dibromo-4-(trifluoromethyl)pyridine SDSbuy 2,6-Dibromo-4-(trifluoromethyl)pyridine2,6-Dibromo-4-(trifluoromethyl)pyridine supplier2,6-Dibromo-4-(trifluoromethyl)pyridine uses2,6-Dibromo-4-(trifluoromethyl)pyridine molecular weightprice of 2,6-Dibromo-4-(trifluoromethyl)pyridine2,6-Dibromo-4-(trifluoromethyl)pyridine chemical name formula of 2,6-Dibromo-4-(trifluoromethyl)pyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label