Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

m-Tolylmethanamine

  • CAS No. 100-81-2

  • Cat. No. CS-W004682
  • Purity≥97%
  • MDL No.MFCD00008118

*For research and further manufacturing use only, not for direct human use.

m-Tolylmethanamine|CS-W004682

Structure of 100-81-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 100-81-2
  • Cat. No. CS-W004682
  • Purity ≥97%
  • MDL No. MFCD00008118
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁N
  • Molecular Weight 121.18
  • Synonym(s) α-Amino-m-xylene
  • SMILES NCC1=CC=CC(C)=C1

Description

3-Methylbenzylamine ({(3-chlorophenyl)methanamine}) has been used as a templating agent in the synthesis of amine-templated materials containing two-dimensional lithium beryllofluoride sheets of the stoichiometry [LiBeF(4)](-). It has also been used to study the chromatographic behavior of a series of substituted aniline and pyridine basic compounds on C18 bonded silica.

Application

m-Tolylmethanamine serves as a versatile building block in medicinal chemistry and catalysis, offering a meta-substituted benzylamine functionality with enhanced lipophilicity and metabolic stability. Its bench-stable nature and compatibility with standard amine coupling reactions facilitate efficient synthesis of target molecules, including kinase inhibitors and bioactive heterocycles. The methyl group provides steric and electronic modulation without compromising reactivity, enabling predictable transformations in multi-step synthetic sequences.

Synthesis

  • Route1
    • null|null
      620-22-4
    • ~77%
    • In-stock
      m-Tolylmethanamine|CS-W004682
      100-81-2

    References

    • Thomas; Collins; Cuzens; Spiciarich; Goralski; Singaram Journal of Organic Chemistry, 2001 , vol. 66, # 6 p. 1999 - 2004
  • Route2

    References

    • US2008/39658 A1, ; Page/Page column 4-6 ;
  • Route3

    References

    • EP1762561 A1, ; Page/Page column 7-8 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H314-H318
Precautionary Statements : P210-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P403-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.45372
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • m-Tolylmethanamine sigmam-Tolylmethanamine manufacturerm-Tolylmethanamine pricem-Tolylmethanamine structurem-Tolylmethanamine SDSbuy m-Tolylmethanaminem-Tolylmethanamine supplierm-Tolylmethanamine usesm-Tolylmethanamine molecular weightprice of m-Tolylmethanaminem-Tolylmethanamine chemical name formula of m-Tolylmethanamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label