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CS-W001157 4
Total: USD 88.00

2-Hydroxymethyltetrahydropyran

  • CAS No. 100-72-1

  • Cat. No. CS-0034490
  • Molecule weight116.16
  • Purity≥98%
  • MDL No.MFCD00006624

*For research and further manufacturing use only, not for direct human use.

2-Hydroxymethyltetrahydropyran|CS-0034490

Structure of 100-72-1

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General Information

  • CAS No. 100-72-1
  • Cat. No. CS-0034490
  • Purity ≥98%
  • MDL No. MFCD00006624
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₂
  • Molecular Weight 116.16
  • Synonym(s) Tetrahydropyran-2-Methanol
  • SMILES OCC1CCCCO1

Description

2-Hydroxymethyltetrahydropyran serves as a versatile chiral synthon in organic synthesis, featuring a pendant hydroxymethyl group that enables selective functionalization. The tetrahydropyran ring provides conformational rigidity and stability under standard conditions, while the hydroxyl moiety facilitates derivatization or protection strategies. This scaffold integrates readily into complex molecular architectures requiring controlled stereochemistry and polar functionality.

Synthesis

  • Route1

    References

    • WO2011/149339 A1, ; Page/Page column 22-23 ;
  • Route2

    References

    • Chemical Communications, , # 4 p. 463 - 464
  • Route3

    References

    • WO2013/101968 A1, ; Page/Page column 25-27 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362-P370+P378-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.5478
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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