DEL B Kit Regular Library
| Cat. No. : CS-LD002 |
|---|
| （100 billion） |
| Library Contents: |
| The discovery of hit molecule is a cornerstone of drug development. Among the diverse tools available, DNA-encoded libraries have emerged a revolutionary platform for high-throughput screening. Compared with traditional HTS, DEL features shorter screening processes, lower costs, simpler assays, and larger library capacities. DEL Construction utilizes split-and-pool synthesis, a combinatorial chemistry approach that involves iterative splitting, reaction, and pooling. This strategy enables rapid, exponential assembly of fragments in minimal steps without the need for individual compound synthesis andassoicicated isolation or purification steps, thus greatly reducing overall costs. The technology enables simultaneous affinity screeningof massive compound collections to target proteins in a single step. By coupling chemical structures with unique DNA barcodes, each compound is tagged with a distinct DNA sequence for convenient tracking and decoding.DELs readily enable the construction and efficient screening of libraries containing millions to billions of compounds. As a result, DEL screening combines the dual advantages of high efficiency and low cost, making DEL a transformative technology in modern drug discovery. The DEL kit consists of 50 independent libraries with a total scale of 100 billion compounds. It is constructed through stepwise combinatorial chemistry strategies involving 2-, 3-, and 4-round synthesis. By employing diverse scaffolds and flexible linking strategies, it encompasses various ring systems, linear frameworks, and heterocyclic structures. Screening can be achieved solely through affinity, independent of target-specific activity detection methods. This library is suitable for DEL screening against a wide range of targets. |
| Size (Pre-dissolved DMSO or Solid) | Stock | Price |
|---|---|---|
| In-stock | Get quote |
Products are for research use only. Not for human use. We do not sell to patients.
Bulk Inquiry
CollapseYour information is safe with us. * Required Fields
Data Sheet
Description & Advantages
Composition
| Formulation: | A DNA encoded kit consist of 50 distinct small molecule DEL libraries, with a molecular scale of up to 100 billion, suitable for hit discovery and capable of providing high-quality starting molecules for drug designing. |
|---|---|
| Container: | 96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode. |
| Storage: | -80°C |
| Shipping: | Blue ice or dry ice |
• A collection of 100 billion compounds can be used for DEL screening.
• Standardized synthesis procedures and quality control protocols to ensure the reliability of compound chemical structures and the accuracy of encoding information, thereby guaranteeing the credibility of screening data.
Browsing History
| Tags:DEL B Kit Regular Library supplier, DEL B Kit Regular Library purchase, DEL B Kit Regular Library manufacturer, DEL B Kit Regular Library sigma, DEL B Kit Regular Library distributor, cost, DEL B Kit Regular Library buy, DEL B Kit Regular Library for sale |