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CS-W001157 4
Total: USD 88.00

(3R)-5-Oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylic acid

  • CAS No. 99735-43-0

  • Cat. No. CS-0053322
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3R)-5-Oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylic acid|CS-0053322

Structure of 99735-43-0

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General Information

  • CAS No. 99735-43-0
  • Cat. No. CS-0053322
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₅NO₃
  • Molecular Weight 233.26
  • Synonym(s) (1R, 3R)-1-(1-Phenylethyl)-5-Oxo-3-Pyrrolidine Carboxylic Acid
  • SMILES C[C@@H](N1C[C@@H](CC1=O)C(O)=O)C1=CC=CC=C1

Synthesis

  • Route1
    • In-stock
      Itaconic acid|CS-0015302
      97-65-4
    • null|null
      3886-69-9
    • ~29%
    • In-stock
      (3R)-5-Oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylic acid|CS-0053322
      99735-43-0

    References

    • ASTRAZENECA AB Patent: US2011/92526 A1, 2011 ; Location in patent: Page/Page column 24 ;
  • Route2
    • Methyl (R)-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylate|CS-0462913
      99735-45-2
    • ~71%
    • In-stock
      (3R)-5-Oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylic acid|CS-0053322
      99735-43-0

    References

    • Culbertson, Townley P.; Domagala, John M.; Nichols, Jeffery B.; Priebe, Stephen; Skeean, Richard W. Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1711 - 1715
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 30, # 10 p. 1711 - 1715

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   57.61
  • LogP   1.6807
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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