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CS-W001157 4
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tert-Butyl (7-aminoheptyl)carbamate

  • CAS No. 99733-18-3

  • Cat. No. CS-0042235
  • Purity≥97%
  • MDL No.MFCD02094498

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (7-aminoheptyl)carbamate|CS-0042235

Structure of 99733-18-3

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General Information

  • CAS No. 99733-18-3
  • Cat. No. CS-0042235
  • Purity ≥97%
  • MDL No. MFCD02094498
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₆N₂O₂
  • Molecular Weight 230.35
  • Synonym(s) tert-Butyl 2,8-diaminooctanoate
  • SMILES O=C(OC(C)(C)C)NCCCCCCCN

Description

tert-Butyl (7-aminoheptyl)carbamate serves as a protected amine handle for peptide synthesis and bioconjugation. The tert-butyl carbamate group enables stable, orthogonal protection under standard conditions, while the aliphatic amine side chain offers flexible spacing for linker integration. This derivative supports efficient coupling workflows with minimal epimerization risk.

Application

tert-Butyl (7-aminoheptyl)carbamate serves as a stable, bench-ready amino protecting group for primary amines, enabling straightforward deprotection under mild acidic conditions. Its aliphatic spacer provides flexibility in peptide and fragment-based synthesis, while the tert-butoxycarbonyl (Boc) moiety offers excellent functional group tolerance and compatibility with standard coupling protocols. Widely used in medicinal chemistry and process development, it facilitates efficient purification and isolation of intermediates.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry, , vol. 14, # 19 p. 6570 - 6580
  • Route2
    • null|null
      62146-55-8
    • ~%
    • In-stock
      tert-Butyl (7-aminoheptyl)carbamate|CS-0042235
      99733-18-3

    References

    • Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 31, p. 1410 - 1415
  • Route3
    • null|null
      1070-19-5
    • ~%
    • In-stock
      tert-Butyl (7-aminoheptyl)carbamate|CS-0042235
      99733-18-3

    References

    • Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 31, p. 1410 - 1415

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.4203
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   7

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