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CS-W001157 4
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6-Methylpiperidine-2-carboxylic acid

  • CAS No. 99571-58-1

  • Cat. No. CS-0039203
  • Purity≥95%
  • MDL No.MFCD00513436

*For research and further manufacturing use only, not for direct human use.

6-Methylpiperidine-2-carboxylic acid|CS-0039203

Structure of 99571-58-1

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General Information

  • CAS No. 99571-58-1
  • Cat. No. CS-0039203
  • Purity ≥95%
  • MDL No. MFCD00513436
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) 2-Piperidinecarboxylicacid, 6-Methyl-
  • SMILES O=C(C1NC(C)CCC1)O

Description

6-Methylpiperidine-2-carboxylic acid features a sterically hindered piperidine core with a methyl group at the 6-position, enhancing metabolic stability. The carboxylic acid functionality provides a polar handle for conjugation and solubility modulation. This scaffold integrates readily into bioactive molecules, offering favorable pharmacokinetic properties in medicinal chemistry applications.

Application

6-Methylpiperidine-2-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and reductive amination protocols. Its tertiary amine functionality and adjacent carboxylic acid facilitate efficient derivatization, while the methyl substitution enhances metabolic stability. The compound exhibits good bench stability and compatibility with common purification methods, making it a practical building block for peptide-like libraries and targeted small-molecule synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.6016
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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