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CS-W001157 4
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3-Methyl-oxetane-3-carbaldehyde

  • CAS No. 99419-31-5

  • Cat. No. CS-W019097
  • Purity≥97%
  • MDL No.MFCD09842436

*For research and further manufacturing use only, not for direct human use.

3-Methyl-oxetane-3-carbaldehyde|CS-W019097

Structure of 99419-31-5

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General Information

  • CAS No. 99419-31-5
  • Cat. No. CS-W019097
  • Purity ≥97%
  • MDL No. MFCD09842436
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈O₂
  • Molecular Weight 100.12
  • Synonym(s) 3-Oxetanecarboxaldehyde, 3-Methyl-
  • SMILES O=CC1(C)COC1

Description

3-Methyl-oxetane-3-carbaldehyde features a strained oxetane ring fused to a methyl-substituted aldehyde, offering enhanced reactivity for conjugate additions and cycloadditions. This bench-stable, moisture-tolerant reagent integrates readily into complex molecular architectures, enabling efficient access to bioactive scaffolds in medicinal chemistry and polymer synthesis.

Application

3-Methyl-oxetane-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles. Its strained oxetane ring enhances metabolic stability, while the aldehyde functionality facilitates diverse transformations including reductive amination, Wittig reactions, and nucleophilic additions. The methyl substituent provides steric control and modulates reactivity, offering improved bench stability and compatibility with standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.2218
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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