6-Bromo-2,3-dimethylpyridine

Name: 6-Bromo-2,3-dimethylpyridine
Brand: ChemScene
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CAS No. 99132-28-2
Cat. No. CS-0197540
Purity≥96%
MDL No.MFCD11869959

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 99132-28-2

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Description

6-Bromo-2,3-dimethylpyridine features a brominated pyridine core with two methyl groups at positions 2 and 3, enabling selective functionalization in cross-coupling reactions. The electron-deficient aromatic ring pairs with the sterically accessible bromine for efficient Pd-catalyzed transformations. This bench-stable derivative serves as a key building block in pharmaceutical synthesis and advanced heterocyclic chemistry.

Application

6-Bromo-2,3-dimethylpyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen functionality. The methyl groups at C2 and C3 provide steric protection and enhance stability, while the pyridine core offers predictable nitrogen coordination for transition metal complexes. This compound facilitates efficient construction of substituted heterocyclic scaffolds with improved bench stability and straightforward purification.

General Information

CAS No. 99132-28-2
Cat. No. CS-0197540
Purity ≥96%
MDL No. MFCD11869959
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈BrN
Molecular Weight 186.05
Synonym(s) 6-BROMO-2,3-DIMETHYL-PYRIDINE
SMILES CC1=CC=C(Br)N=C1C

Computational Chemistry Data

TPSA 12.89
LogP 2.46094
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1760
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P305+P351+P338-P330-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-2,3-dimethylpyridine

CAS No. 99132-28-2

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