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CS-W001157 4
Total: USD 88.00

3-Hydroxybenzoic acid

  • CAS No. 99-06-9

  • Cat. No. CS-W004049
  • Molecule weight138.12
  • Purity≥98%
  • MDL No.MFCD00002506

*For research and further manufacturing use only, not for direct human use.

3-Hydroxybenzoic acid|CS-W004049

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General Information

  • CAS No. 99-06-9
  • Cat. No. CS-W004049
  • Purity ≥98%
  • MDL No. MFCD00002506
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆O₃
  • Molecular Weight 138.12
  • Synonym(s) m-Hydroxybenzoic acid
  • SMILES OC(C1=CC(O)=CC=C1)=O

Application

3-Hydroxybenzoic acid serves as a versatile building block in synthetic organic chemistry, enabling access to substituted benzoic acid derivatives and functionalized heterocycles. Its ortho-hydroxyl group facilitates intramolecular hydrogen bonding, enhancing stability and influencing reactivity in electrophilic substitution and coupling reactions. The molecule exhibits excellent bench stability and compatibility with common protecting group strategies, making it a reliable intermediate for pharmaceutical and agrochemical synthesis workflows.

Synthesis

  • Route1

    References

    • Chen, Junmin; Yuan, Tangjun; Hao, Wenyan; Cai, Mingzhong Catalysis Communications, 2011 , vol. 12, # 15 p. 1463 - 1465
  • Route2

    References

    • Yang, Daoshan; An, Baojuan; Wei, Wei; Jiang, Min; You, Jinmao; Wang, Hua Tetrahedron, 2014 , vol. 70, # 22 p. 3630 - 3634
  • Route3

    References

    • Xiao, Yan; Xu, Yongnan; Cheon, Hwan-Sung; Chae, Junghyun Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5804 - 5809

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.0904
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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