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CS-W001157 4
Total: USD 88.00

2-Iodo-3-methoxyaniline

  • CAS No. 98991-09-4

  • Cat. No. CS-0160017
  • Purity≥97%
  • MDL No.MFCD11848601
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Iodo-3-methoxyaniline|CS-0160017

Structure of 98991-09-4

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Description

2-Iodo-3-methoxyaniline delivers a reactive iodine handle paired with an electron-donating methoxy group, enabling efficient cross-coupling transformations. This ortho-substituted aryl iodide exhibits enhanced stability and solubility in polar organic solvents, facilitating use in palladium-catalyzed reactions. The strategic positioning of the methoxy moiety modulates electronic properties for selective functionalization.

Application

2-Iodo-3-methoxyaniline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its iodine functionality. The methoxy group provides moderate electron-donating character and enhances solubility, while the aniline scaffold offers compatibility with standard protecting group strategies. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis workflows in API development and heterocycle construction.

General Information

  • CAS No. 98991-09-4
  • Cat. No. CS-0160017
  • Purity ≥97%
  • MDL No. MFCD11848601
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈INO
  • Molecular Weight 249.05
  • Synonym(s) Benzenamine, 2-iodo-3-methoxy-
  • SMILES NC1=CC=CC(OC)=C1I

Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.882
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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