Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Iodo-3-methoxyaniline

  • CAS No. 98991-09-4

  • Cat. No. CS-0160017
  • Purity≥97%
  • MDL No.MFCD11848601

*For research and further manufacturing use only, not for direct human use.

2-Iodo-3-methoxyaniline|CS-0160017

Structure of 98991-09-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 98991-09-4
  • Cat. No. CS-0160017
  • Purity ≥97%
  • MDL No. MFCD11848601
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈INO
  • Molecular Weight 249.05
  • Synonym(s) Benzenamine, 2-iodo-3-methoxy-
  • SMILES NC1=CC=CC(OC)=C1I

Description

2-Iodo-3-methoxyaniline delivers a reactive iodine handle paired with an electron-donating methoxy group, enabling efficient cross-coupling transformations. This ortho-substituted aryl iodide exhibits enhanced stability and solubility in polar organic solvents, facilitating use in palladium-catalyzed reactions. The strategic positioning of the methoxy moiety modulates electronic properties for selective functionalization.

Application

2-Iodo-3-methoxyaniline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its iodine functionality. The methoxy group provides moderate electron-donating character and enhances solubility, while the aniline scaffold offers compatibility with standard protecting group strategies. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis workflows in API development and heterocycle construction.

Synthesis

  • Route1
    • null|null
      194869-14-2
    • ~96%
    • In-stock
      2-Iodo-3-methoxyaniline|CS-0160017
      98991-09-4

    References

    • Jia, Yanxing; Zhu, Jieping Synlett, 2005 , # 16 art. no. G22605ST, p. 2469 - 2472
  • Route2

    References

    • Hine, Jack; Hahn, Soonkap; Miles, David E.; Ahn, Kyunghye Journal of Organic Chemistry, 1985 , vol. 50, # 25 p. 5092 - 5096
  • Route3
    • 2-Iodo-3-nitrophenol|CS-0098506
      197243-48-4
    • ~%
    • In-stock
      2-Iodo-3-methoxyaniline|CS-0160017
      98991-09-4

    References

    • Tullberg, Erik; Schacher, Felix; Peters, Dan; Frejd, Torbjoern Synthesis, 2006 , # 7 p. 1183 - 1189

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.882
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Iodo-3-methoxyaniline sigma2-Iodo-3-methoxyaniline manufacturer2-Iodo-3-methoxyaniline price2-Iodo-3-methoxyaniline structure2-Iodo-3-methoxyaniline SDSbuy 2-Iodo-3-methoxyaniline2-Iodo-3-methoxyaniline supplier2-Iodo-3-methoxyaniline uses2-Iodo-3-methoxyaniline molecular weightprice of 2-Iodo-3-methoxyaniline2-Iodo-3-methoxyaniline chemical name formula of 2-Iodo-3-methoxyaniline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label