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Structure of 98730-77-9
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1-(Hydroxymethyl)cyclopropanecarbonitrile features a strained cyclopropyl ring bearing both a nitrile and hydroxymethyl group, enabling unique reactivity in synthetic transformations. This configuration supports efficient functionalization at the ring junction, delivering access to complex heterocyclic scaffolds under mild conditions. The molecule exhibits enhanced stability and solubility in polar solvents, facilitating use in iterative synthesis workflows.
1-(Hydroxymethyl)cyclopropanecarbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized cyclopropyl scaffolds. The molecule combines a nitrile group for downstream transformations—such as amide or carboxylic acid derivatization—with a primary alcohol that facilitates conjugation, protection, or oxidation. Its rigid cyclopropyl core enhances metabolic stability and modulates physicochemical properties. Bench-stable and compatible with standard synthetic protocols, it functions effectively in multi-step syntheses of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: