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CS-W001157 4
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S-(6-Aminohexyl) ethanethioate hydrochloride

  • CAS No. 98486-87-4

  • Cat. No. CS-0437379
  • Molecule weight211.75
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

S-(6-Aminohexyl) ethanethioate hydrochloride|CS-0437379

Structure of 98486-87-4

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General Information

  • CAS No. 98486-87-4
  • Cat. No. CS-0437379
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈ClNOS
  • Molecular Weight 211.75
  • Synonym(s) 1-[(6-Aminohexyl)sulfanyl]ethan-1-one hydrochloride
  • SMILES O=C(C)SCCCCCCN.Cl

Description

S-(6-Aminohexyl) ethanethioate hydrochloride features a primary amine at one terminus and a thiol group at the other, enabling dual conjugation chemistry. The hydrochloride salt enhances solubility and stability in aqueous buffers, facilitating efficient coupling to maleimides, gold surfaces, or cysteine residues under mild conditions. This bifunctional reagent streamlines site-specific bioconjugation workflows.

Application

S-(6-Aminohexyl) ethanethioate hydrochloride serves as a versatile bifunctional building block for conjugation and polymer synthesis. The primary amine enables efficient coupling reactions, while the thiol group facilitates site-specific attachment via Michael addition or gold-catalyzed thiol-ene chemistry. Its hydrochloride salt form enhances solubility and stability in aqueous and protic media, simplifying handling and purification in synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H315-H318-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   2.207
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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