Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Ethyl 2,4,5-trifluorobenzoylacetate

  • CAS No. 98349-24-7

  • Cat. No. CS-0033524
  • Purity≥97%
  • MDL No.MFCD00792431

*For research and further manufacturing use only, not for direct human use.

Ethyl 2,4,5-trifluorobenzoylacetate|CS-0033524

Structure of 98349-24-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 98349-24-7
  • Cat. No. CS-0033524
  • Purity ≥97%
  • MDL No. MFCD00792431
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉F₃O₃
  • Molecular Weight None
  • Synonym(s) Ethyl 3-Oxo-3-(2,4,5-trifluorophenyl)propanoate
  • SMILES FC1=CC(F)=C(F)C=C1C(CC(OCC)=O)=O

Description

Ethyl 2,4,5-trifluorobenzoylacetate features a trifluorinated aromatic ring that imparts enhanced electron deficiency and metabolic stability. This structural motif enables efficient coupling in C–C bond formation reactions, particularly in transition-metal-catalyzed cross-couplings. The ester functionality offers tunable reactivity and compatibility with diverse synthetic transformations.

Application

Ethyl 2,4,5-trifluorobenzoylacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to fluorinated heterocycles and bioactive scaffolds. Its α-acyl ketone functionality supports facile enolization and Michael addition reactions, while the trifluoromethyl-substituted aromatic ring enhances metabolic stability and lipophilicity. The ester group facilitates purification and downstream transformations, offering robust bench stability and compatibility with standard coupling and cyclization protocols.

Synthesis

  • Route1

    References

    • Jung, Michael E.; Yang, Eric C.; Vu, Binh T.; Kiankarimi, Mehrak; Spyrou, Emmanouil; Kaunitz, Jon Journal of Medicinal Chemistry, 1999 , vol. 42, # 19 p. 3899 - 3909
  • Route2

    References

    • LG LIFE SCIENCES LTD. Patent: WO2007/64077 A1, 2007 ; Location in patent: Page/Page column 8 ;
  • Route3

    References

    • Hay, Alastair M.; Hobbs-Dewitt, Sheila; MacDonald, Alasdair A.; Ramage, Robert Synthesis, 1999 , # 11 p. 1979 - 1985

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.37
  • LogP   2.2398
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Ethyl 2,4,5-trifluorobenzoylacetate sigmaEthyl 2,4,5-trifluorobenzoylacetate manufacturerEthyl 2,4,5-trifluorobenzoylacetate priceEthyl 2,4,5-trifluorobenzoylacetate structureEthyl 2,4,5-trifluorobenzoylacetate SDSbuy Ethyl 2,4,5-trifluorobenzoylacetateEthyl 2,4,5-trifluorobenzoylacetate supplierEthyl 2,4,5-trifluorobenzoylacetate usesEthyl 2,4,5-trifluorobenzoylacetate molecular weightprice of Ethyl 2,4,5-trifluorobenzoylacetateEthyl 2,4,5-trifluorobenzoylacetate chemical name formula of Ethyl 2,4,5-trifluorobenzoylacetate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label