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CS-W001157 4
Total: USD 88.00

2,4-Diaminobenzaldehyde

  • CAS No. 98276-57-4

  • Cat. No. CS-0039250
  • Purity≥97%
  • MDL No.MFCD02094162

*For research and further manufacturing use only, not for direct human use.

2,4-Diaminobenzaldehyde|CS-0039250

Structure of 98276-57-4

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General Information

  • CAS No. 98276-57-4
  • Cat. No. CS-0039250
  • Purity ≥97%
  • MDL No. MFCD02094162
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O
  • Molecular Weight 136.15
  • Synonym(s) 2,4-DIAMINO BENZALDEHYDE
  • SMILES O=CC1=CC=C(N)C=C1N

Description

2,4-Diaminobenzaldehyde features two amino groups flanking a reactive aldehyde moiety, enabling selective conjugation in bioconjugation and fluorescent probe design. This electron-rich scaffold supports efficient imine formation under mild conditions and exhibits enhanced solubility in aqueous and polar organic solvents.

Application

2,4-Diaminobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling the synthesis of heterocyclic scaffolds via condensation and cyclization reactions. Its ortho-diamino functionality facilitates metal coordination and offers robust reactivity in Ugi-type multicomponent reactions. The aldehyde group supports facile derivatization through imine formation and reductive amination, while the compound exhibits good bench stability and ease of purification—key attributes for high-throughput screening and process-scale applications.

Synthesis

  • Route1
    • null|null
      528-75-6
    • ~90%
    • In-stock
      2,4-Diaminobenzaldehyde|CS-0039250
      98276-57-4

    References

    • Merlic, Craig A.; Motamed, Soheil; Quinn, Bruce Journal of Organic Chemistry, 1995 , vol. 60, # 11 p. 3365 - 3369
  • Route2

    References

    • Wani; Nicholas; Manikumar; Wall Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1774 - 1779
  • Route3
    • 4-Amino-2-nitrobenzaldehyde|CS-0119716
      102170-39-8
    • ~%
    • In-stock
      2,4-Diaminobenzaldehyde|CS-0039250
      98276-57-4

    References

    • Ricci Annali di Chimica (Rome, Italy), 1958 , vol. 48, p. 985,993

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.11
  • LogP   0.6635
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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