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CS-W001157 4
Total: USD 88.00

Boc-D-3-Pal-OH

  • CAS No. 98266-33-2

  • Cat. No. CS-W014590
  • Purity≥97%
  • MDL No.MFCD00076901

*For research and further manufacturing use only, not for direct human use.

Boc-D-3-Pal-OH|CS-W014590

Structure of 98266-33-2

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General Information

  • CAS No. 98266-33-2
  • Cat. No. CS-W014590
  • Purity ≥97%
  • MDL No. MFCD00076901
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈N₂O₄
  • Molecular Weight 266.29
  • Synonym(s) None
  • SMILES O=C([C@@H](CC1=CC=CN=C1)NC(OC(C)(C)C)=O)O

Description

Boc-D-3-Pal-OH features a protected D-3-palmitic acid derivative with enhanced stability and solubility in organic solvents. This bench-stable reagent integrates seamlessly into peptide synthesis workflows, enabling efficient incorporation of hydrophobic side chains. The Boc group facilitates straightforward deprotection under mild acidic conditions, while the primary alcohol supports further functionalization.

Application

Boc-D-3-Pal-OH serves as a key chiral building block for the synthesis of bioactive peptides and heterocyclic scaffolds. The Boc-protected D-3-phenylalanine moiety offers enhanced stability and compatibility with standard peptide coupling protocols, enabling efficient incorporation into complex molecular architectures. Its orthogonality to other functional groups and favorable purification profile make it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Rivier, Jean E.; Porter, John; Rivier, Catherine L.; Perrin, Marylin; Corrigan, Anne; et al. Journal of Medicinal Chemistry, 1986 , vol. 29, # 10 p. 1846 - 1851
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      500-22-1
    • ~%
    • In-stock
      Boc-D-3-Pal-OH|CS-W014590
      98266-33-2

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 26 p. 7592 - 7595
  • Route3
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      102913-22-4
    • ~%
    • In-stock
      Boc-D-3-Pal-OH|CS-W014590
      98266-33-2

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 26 p. 7592 - 7595

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   88.52
  • LogP   1.602
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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