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CS-W001157 4
Total: USD 88.00

(3S,4S)-4-((tert-Butoxycarbonyl)amino)-5-cyclohexyl-3-hydroxypentanoic acid

  • CAS No. 98105-45-4

  • Cat. No. CS-0356875
  • Purity95+%
  • MDL No.MFCD00155624

*For research and further manufacturing use only, not for direct human use.

(3S,4S)-4-((tert-Butoxycarbonyl)amino)-5-cyclohexyl-3-hydroxypentanoic acid|CS-0356875

Structure of 98105-45-4

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General Information

  • CAS No. 98105-45-4
  • Cat. No. CS-0356875
  • Purity 95+%
  • MDL No. MFCD00155624
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₉NO₅
  • Molecular Weight 315.41
  • Synonym(s) Boc-achpa
  • SMILES CC(C)(C)OC(N[C@H]([C@@H](O)CC(O)=O)CC1CCCCC1)=O

Synthesis

  • Route1
    • null|null
      98105-43-2
    • ~94%
    • (3S,4S)-4-((tert-Butoxycarbonyl)amino)-5-cyclohexyl-3-hydroxypentanoic acid|CS-0356875
      98105-45-4

    References

    • Boger, Joshua; Payne, Linda S.; Perlow, Debra S.; Lohr, Nancy S.; Poe, Martin; et al. Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1779 - 1790
  • Route2
    • (3s,4s)-4-((Tert-butoxycarbonyl)amino)-3-hydroxy-5-phenylpentanoic acid|CS-0670736
      72155-48-7
    • ~%
    • (3S,4S)-4-((tert-Butoxycarbonyl)amino)-5-cyclohexyl-3-hydroxypentanoic acid|CS-0356875
      98105-45-4

    References

    • Chemical and Pharmaceutical Bulletin, , vol. 38, # 1 p. 103 - 109
  • Route3
    • BOC-L-Phenylalanine Bortezomib Impurity|CS-0169695
      13734-34-4
    • ~%
    • (3S,4S)-4-((tert-Butoxycarbonyl)amino)-5-cyclohexyl-3-hydroxypentanoic acid|CS-0356875
      98105-45-4

    References

    • Journal of Medicinal Chemistry, , vol. 28, # 12 p. 1779 - 1790

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   95.86
  • LogP   2.6857
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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