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Structure of 98-37-3
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3-Amino-4-hydroxybenzenesulfonic acid features a sulfonic acid group that enhances water solubility and provides strong acidity, while the amino and hydroxyl substituents offer versatile sites for coupling reactions. This combination enables efficient integration into dye intermediates and functionalized polymers under mild conditions.
3-Amino-4-hydroxybenzenesulfonic acid serves as a versatile building block for sulfonamide-directed heterocycle synthesis and functionalized aromatic systems. Its ortho-dihydroxy-amino substitution pattern enables reliable coupling reactions, including Ullmann-type C–N bond formations and electrophilic aromatic substitutions. The molecule exhibits good bench stability and facilitates straightforward purification via crystallization or ion-exchange chromatography, making it suitable for scale-up in API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2585
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: