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CS-W001157 4
Total: USD 88.00

3-Amino-4-hydroxybenzenesulfonic acid

  • CAS No. 98-37-3

  • Cat. No. CS-W015950
  • Purity≥95%
  • MDL No.MFCD00007696

*For research and further manufacturing use only, not for direct human use.

3-Amino-4-hydroxybenzenesulfonic acid|CS-W015950

Structure of 98-37-3

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General Information

  • CAS No. 98-37-3
  • Cat. No. CS-W015950
  • Purity ≥95%
  • MDL No. MFCD00007696
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₄S
  • Molecular Weight 189.19
  • Synonym(s) 4-Hydroxymetanilic Acid Hydrate
  • SMILES O=S(C1=CC=C(O)C(N)=C1)(O)=O

Description

3-Amino-4-hydroxybenzenesulfonic acid features a sulfonic acid group that enhances water solubility and provides strong acidity, while the amino and hydroxyl substituents offer versatile sites for coupling reactions. This combination enables efficient integration into dye intermediates and functionalized polymers under mild conditions.

Application

3-Amino-4-hydroxybenzenesulfonic acid serves as a versatile building block for sulfonamide-directed heterocycle synthesis and functionalized aromatic systems. Its ortho-dihydroxy-amino substitution pattern enables reliable coupling reactions, including Ullmann-type C–N bond formations and electrophilic aromatic substitutions. The molecule exhibits good bench stability and facilitates straightforward purification via crystallization or ion-exchange chromatography, making it suitable for scale-up in API intermediate development.

Synthesis

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    • In-stock
      3-Amino-4-hydroxybenzenesulfonic acid|CS-W015950
      98-37-3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 205, p. 51
  • Route2
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      95-55-6
    • ~%
    • In-stock
      3-Amino-4-hydroxybenzenesulfonic acid|CS-W015950
      98-37-3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 205, p. 51
  • Route3
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      7664-93-9
    • null|null
      95-55-6
    • ~%
    • In-stock
      3-Amino-4-hydroxybenzenesulfonic acid|CS-W015950
      98-37-3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 205, p. 51

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2585
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   100.62
  • LogP   0.2211
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   1

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