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CS-W001157 4
Total: USD 88.00

1-(3,5-Dimethoxyphenyl)ethanamine

  • CAS No. 97294-78-5

  • Cat. No. CS-0187792
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(3,5-Dimethoxyphenyl)ethanamine|CS-0187792

Structure of 97294-78-5

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General Information

  • CAS No. 97294-78-5
  • Cat. No. CS-0187792
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅NO₂
  • Molecular Weight 181.23
  • Synonym(s) 3,5-dimethoxy-α-methylbenzylamine
  • SMILES CC(C1=CC(=CC(=C1)OC)OC)N

Description

1-(3,5-Dimethoxyphenyl)ethanamine features a benzene ring bearing two methoxy groups at the 3- and 5-positions, enhancing solubility and metabolic stability. This electron-rich arylamine integrates readily into bioactive scaffolds, serving as a key building block for pharmaceutical intermediates and functional materials.

Application

1-(3,5-Dimethoxyphenyl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard amine functionalization. Its electron-rich aromatic core and stable benzylic amine functionality offer excellent compatibility with coupling reactions, reductive amination, and electrophilic substitution. The dimethoxy substituents enhance solubility and modulate electronic properties, while the compound exhibits good bench stability and ease of purification—ideal for iterative synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.7235
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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