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Structure of 960371-08-8
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5-Fluoropyridine-2-acetonitrile features a fluorinated pyridine core paired with a reactive acetonitrile group, enabling direct functionalization in synthetic transformations. This electron-deficient heterocycle facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions under mild conditions. The nitrile moiety offers versatility for downstream derivatization via hydrolysis or reduction. Bench-stable and moisture-tolerant, it serves as a robust building block for pharmaceutical intermediates and agrochemical scaffolds.
5-Fluoropyridine-2-acetonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated heterocyclic scaffolds through nucleophilic substitution and transition-metal-catalyzed coupling reactions. Its acetonitrile group facilitates functionalization via hydrolysis or reduction, while the fluorine substituent enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and compatibility with standard synthetic workflows, making it valuable for the synthesis of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3276
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: