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CS-W001157 4
Total: USD 88.00

2,5-Dibromoisonicotinaldehyde

  • CAS No. 959244-28-1

  • Cat. No. CS-0092869
  • Purity≥98%
  • MDL No.MFCD10574709

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromoisonicotinaldehyde|CS-0092869

Structure of 959244-28-1

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General Information

  • CAS No. 959244-28-1
  • Cat. No. CS-0092869
  • Purity ≥98%
  • MDL No. MFCD10574709
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Br₂NO
  • Molecular Weight 264.90
  • Synonym(s) 2,5-Dibromopyridine-4-carboxaldehyde
  • SMILES O=CC1=CC(Br)=NC=C1Br

Description

2,5-Dibromoisonicotinaldehyde features a pyridine core bearing bromine substituents at the 2 and 5 positions, enhancing electrophilicity at the aldehyde carbon. This electron-deficient scaffold enables efficient coupling in cross-coupling reactions and serves as a key building block for functionalized heterocycles in medicinal chemistry and materials science.

Application

2,5-Dibromoisonicotinaldehyde serves as a versatile building block in synthetic organic chemistry, enabling the construction of brominated heterocyclic scaffolds via coupling and cyclization reactions. Its aldehyde functionality facilitates efficient derivatization, while the strategically positioned bromine atoms support palladium-catalyzed cross-coupling processes. The compound exhibits good bench stability and is readily purified by column chromatography, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.4191
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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