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Structure of 955400-58-5
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This pyridazinyl-thiazole carboxylic acid integrates a rigid heteroaromatic core with a reactive carboxylate handle, enabling direct coupling in peptide and macrocycle synthesis. The electron-deficient pyridazine ring enhances reactivity in nucleophilic substitution, while the thiazole moiety provides metabolic stability and favorable solubility under standard conditions.
2-(Pyridazin-4-yl)thiazole-4-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its pyridazinyl-thiazole scaffold provides enhanced rigidity and polarity, enabling efficient integration into bioactive molecules. The carboxylic acid group facilitates direct derivatization via amide coupling or esterification, while the molecule exhibits good bench stability and solubility in common organic solvents, supporting scalable synthesis and purification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: