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CS-W001157 4
Total: USD 88.00

4-Methoxy-TEMPO

  • CAS No. 95407-69-5

  • Cat. No. CS-0179377
  • Purity≥97%
  • MDL No.MFCD00270334

*For research and further manufacturing use only, not for direct human use.

4-Methoxy-TEMPO|CS-0179377

Structure of 95407-69-5

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General Information

  • CAS No. 95407-69-5
  • Cat. No. CS-0179377
  • Purity ≥97%
  • MDL No. MFCD00270334
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀NO₂
  • Molecular Weight 186.27
  • Synonym(s) Methoxytetramethylpiperidineoxyl
  • SMILES COC(CC1(C)C)CC(C)(N1[O])C

Description

4-Methoxy-TEMPO is a bench-stable nitroxide radical featuring a methoxy group at the para position, enhancing solubility and electronic modulation. This derivative enables efficient catalytic oxidation processes and radical stabilization in synthetic transformations.

Application

4-Methoxy-TEMPO serves as a stable, bench-friendly nitroxyl radical reagent enabling selective oxidation of alcohols to carbonyl compounds under mild conditions. Its methoxy substituent enhances solubility and functional group tolerance, facilitating clean reactions in complex molecule synthesis. The compound functions reliably in catalytic oxidation protocols and offers improved handling over traditional TEMPO derivatives.

Synthesis

  • Route1
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      45985-24-8
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      74-88-4
    • ~88%
    • In-stock
      4-Methoxy-TEMPO|CS-0179377
      95407-69-5

    References

    • Miyazawa, Takeo; Endo, Takeshi; Shiihashi, Shigeo; Okawara, Makoto Journal of Organic Chemistry, 1985 , vol. 50, # 8 p. 1332 - 1334
  • Route2
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      90246-27-8
    • ~%
    • In-stock
      4-Methoxy-TEMPO|CS-0179377
      95407-69-5

    References

    • Journal of the American Chemical Society, , vol. 106, # 13 p. 3877 - 3878
  • Route3
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      131452-29-4
    • ~%
    • In-stock
      4-Methoxy-TEMPO|CS-0179377
      95407-69-5

    References

    • Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 68, # 3 p. 239 - 244

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   32.7
  • LogP   2.0436
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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