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CS-W001157 4
Total: USD 88.00

4-Amino-5-methylpyridin-2-ol

  • CAS No. 95306-64-2

  • Cat. No. CS-W022074
  • Purity≥98%
  • MDL No.MFCD12546373

*For research and further manufacturing use only, not for direct human use.

4-Amino-5-methylpyridin-2-ol|CS-W022074

Structure of 95306-64-2

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General Information

  • CAS No. 95306-64-2
  • Cat. No. CS-W022074
  • Purity ≥98%
  • MDL No. MFCD12546373
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 4-amino-5-methylpyridine-2(1H)-one
  • SMILES O=C1C=C(N)C(C)=CN1

Description

4-Amino-5-methylpyridin-2-ol is a heterocyclic scaffold featuring a pyridinol core with strategically positioned amino and methyl groups. This configuration enables robust conjugation in synthetic transformations, particularly in metal-catalyzed cross-coupling reactions. The molecule exhibits enhanced solubility and stability under standard conditions, facilitating efficient integration into complex molecular architectures.

Application

4-Amino-5-methylpyridin-2-ol serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridine-based scaffolds relevant in medicinal chemistry. Its ortho-diol and amino functionalities offer complementary reactivity for coupling reactions, protecting group strategies, and metal-catalyzed transformations. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis and process development workflows.

Synthesis

  • Route1
    • null|null
      95306-62-0
    • ~78%
    • In-stock
      4-Amino-5-methylpyridin-2-ol|CS-W022074
      95306-64-2

    References

    • Nguyen Chi Hung; Bisagni, Emile Synthesis, 1984 , # 9 p. 765 - 766
  • Route2

    References

    • Nguyen Chi Hung; Bisagni, Emile Synthesis, 1984 , # 9 p. 765 - 766
  • Route3
    • 6-Chloro-4-hydroxy-5-methylpyridin-2(1H)-one hydrochloride|CS-0547330
      95306-65-3
    • ~%
    • In-stock
      4-Amino-5-methylpyridin-2-ol|CS-W022074
      95306-64-2

    References

    • Nguyen Chi Hung; Bisagni, Emile Synthesis, 1984 , # 9 p. 765 - 766

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.88
  • LogP   0.26552
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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