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CS-W001157 4
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5,7-Dichloro-3-methylthieno[3,2-b]pyridine

  • CAS No. 952435-06-2

  • Cat. No. CS-0197611
  • Molecule weight218.10
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,7-Dichloro-3-methylthieno[3,2-b]pyridine|CS-0197611

Structure of 952435-06-2

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General Information

  • CAS No. 952435-06-2
  • Cat. No. CS-0197611
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅Cl₂NS
  • Molecular Weight 218.10
  • Synonym(s) None
  • SMILES CC1=CSC2=C1N=C(C=C2Cl)Cl

Description

5,7-Dichloro-3-methylthieno[3,2-b]pyridine features a fused heterocyclic core with electron-deficient character, enabling robust coupling reactions in synthetic medicinal chemistry. The dichloro substitution enhances electrophilicity at key positions, while the methyl group provides steric and electronic modulation. This scaffold integrates readily into complex molecular architectures under standard conditions.

Application

5,7-Dichloro-3-methylthieno[3,2-b]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its electron-deficient core enables efficient coupling reactions, while the methyl group provides a site for further functionalization. The molecule exhibits good bench stability and facilitates the construction of complex scaffolds via cross-coupling or nucleophilic substitution protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.91152
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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