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Structure of 947249-44-7
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Methyl 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate delivers a boronate-functionalized pyridine scaffold with enhanced stability and solubility. This bench-stable reagent integrates seamlessly into Suzuki-Miyaura coupling workflows, enabling efficient C–C bond formation at ambient conditions. The para-aminopyridine motif provides a versatile handle for downstream derivatization.
Methyl 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinate serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient coupling under mild conditions, while the pyridine nitrogen and ester functionality offer orthogonal reactivity for downstream modifications. Bench-stable and easily purified, it facilitates rapid access to substituted nicotinamide derivatives and heterocyclic scaffolds relevant to medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: