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Structure of 944900-06-5
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2-Chloro-6-(trifluoromethyl)nicotinaldehyde features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the chloro substituent fine-tunes reactivity. This aldehyde serves as a key building block in medicinal chemistry, enabling direct coupling reactions under mild conditions. The molecule exhibits excellent bench stability and compatibility with diverse synthetic transformations.
2-Chloro-6-(trifluoromethyl)nicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via condensation and cyclization reactions. Its electron-deficient pyridine core enhances reactivity in nucleophilic additions, while the trifluoromethyl group imparts metabolic stability and modulates lipophilicity. Bench-stable and readily purified by distillation, it facilitates scalable synthesis of bioactive intermediates for drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: