Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-6-fluoro-2-pyridinamine

  • CAS No. 944401-65-4

  • Cat. No. CS-0040534
  • Purity≥97%
  • MDL No.MFCD11848480

*For research and further manufacturing use only, not for direct human use.

5-Bromo-6-fluoro-2-pyridinamine|CS-0040534

Structure of 944401-65-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 944401-65-4
  • Cat. No. CS-0040534
  • Purity ≥97%
  • MDL No. MFCD11848480
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrFN₂
  • Molecular Weight 191.00
  • Synonym(s) 5-Bromo-6-fluoropyridin-2-amine
  • SMILES NC1=NC(F)=C(Br)C=C1

Description

5-Bromo-6-fluoro-2-pyridinamine features a strategically positioned bromo and fluoro substitution on the pyridine ring, enabling selective coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds, offering enhanced metabolic stability and tunable polarity for medicinal chemistry applications.

Application

5-Bromo-6-fluoro-2-pyridinamine serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its orthogonal halogenation pattern enables selective metal-coupling reactions, while the pyridinamine functionality facilitates direct derivatization via amidation or electrophilic substitution. The compound exhibits excellent bench stability and compatibility with standard cross-coupling protocols, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Sandell, Johan Journal of Labelled Compounds and Radiopharmaceuticals, 2013 , vol. 56, # 6 p. 321 - 324

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.5654
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-6-fluoro-2-pyridinamine sigma5-Bromo-6-fluoro-2-pyridinamine manufacturer5-Bromo-6-fluoro-2-pyridinamine price5-Bromo-6-fluoro-2-pyridinamine structure5-Bromo-6-fluoro-2-pyridinamine SDSbuy 5-Bromo-6-fluoro-2-pyridinamine5-Bromo-6-fluoro-2-pyridinamine supplier5-Bromo-6-fluoro-2-pyridinamine uses5-Bromo-6-fluoro-2-pyridinamine molecular weightprice of 5-Bromo-6-fluoro-2-pyridinamine5-Bromo-6-fluoro-2-pyridinamine chemical name formula of 5-Bromo-6-fluoro-2-pyridinamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label