Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,4-Difluorobutanoic acid

  • CAS No. 944328-72-7

  • Cat. No. CS-0375270
  • Purity≥95%
  • MDL No.MFCD11110319

*For research and further manufacturing use only, not for direct human use.

4,4-Difluorobutanoic acid|CS-0375270

Structure of 944328-72-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 944328-72-7
  • Cat. No. CS-0375270
  • Purity ≥95%
  • MDL No. MFCD11110319
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆F₂O₂
  • Molecular Weight 124.09
  • Synonym(s) None
  • SMILES O=C(CCC(F)F)O

Description

4,4-Difluorobutanoic acid features a fluorinated aliphatic chain with two electronegative fluorine atoms at the terminal carbon, enhancing metabolic stability and lipophilicity. This configuration imparts unique electronic and steric properties, enabling its use in bioactive molecule design, particularly as a metabolically resistant analog in medicinal chemistry applications.

Application

4,4-Difluorobutanoic acid serves as a valuable building block in medicinal chemistry, enabling the introduction of a metabolically stable, electron-withdrawing difluoromethylene unit adjacent to a carboxylic acid. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient incorporation into bioactive molecules. The gem-difluoro motif enhances lipophilicity and modulates pKa, offering improved metabolic resistance in drug candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H314
Precautionary Statements : P210-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.1163
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4,4-Difluorobutanoic acid sigma4,4-Difluorobutanoic acid manufacturer4,4-Difluorobutanoic acid price4,4-Difluorobutanoic acid structure4,4-Difluorobutanoic acid SDSbuy 4,4-Difluorobutanoic acid4,4-Difluorobutanoic acid supplier4,4-Difluorobutanoic acid uses4,4-Difluorobutanoic acid molecular weightprice of 4,4-Difluorobutanoic acid4,4-Difluorobutanoic acid chemical name formula of 4,4-Difluorobutanoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label