2-Chloro-1,3-thiazole-4-carbonitrile

Name: 2-Chloro-1,3-thiazole-4-carbonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 944124-72-5
Cat. No. CS-0054448
Purity≥96%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-1,3-thiazole-4-carbonitrile|CS-0054448

Structure of 944124-72-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 944124-72-5
Cat. No. CS-0054448
Purity ≥96%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄HClN₂S
Molecular Weight 144.58
Synonym(s) 2-Chlorothiazole-4-carbonitrile
SMILES N#CC1=CSC(Cl)=N1

Description

2-Chloro-1,3-thiazole-4-carbonitrile features a dual functionalization pattern with chlorine and nitrile groups at adjacent positions on the thiazole ring. This electron-deficient heterocycle serves as a key scaffold for medicinal chemistry applications, enabling direct incorporation into bioactive molecules through nucleophilic substitution or transition-metal-catalyzed coupling reactions.

Application

2-Chloro-1,3-thiazole-4-carbonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized thiazole scaffolds. Its dual electrophilic sites—chlorine at C2 and nitrile at C4—facilitate sequential nucleophilic substitutions, palladium-catalyzed couplings, and cyclization reactions. The compound exhibits good bench stability and is compatible with common reaction conditions, making it valuable for medicinal chemistry campaigns and API intermediate development.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 36.68
LogP 1.66818
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

2-Chloro-1,3-thiazole-4-carbonitrile sigma2-Chloro-1,3-thiazole-4-carbonitrile manufacturer2-Chloro-1,3-thiazole-4-carbonitrile price2-Chloro-1,3-thiazole-4-carbonitrile structure2-Chloro-1,3-thiazole-4-carbonitrile SDSbuy 2-Chloro-1,3-thiazole-4-carbonitrile2-Chloro-1,3-thiazole-4-carbonitrile supplier2-Chloro-1,3-thiazole-4-carbonitrile uses2-Chloro-1,3-thiazole-4-carbonitrile molecular weightprice of 2-Chloro-1,3-thiazole-4-carbonitrile2-Chloro-1,3-thiazole-4-carbonitrile chemical name formula of 2-Chloro-1,3-thiazole-4-carbonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-1,3-thiazole-4-carbonitrile

CAS No. 944124-72-5

Recommended Products