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Structure of 943830-81-7
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3-Bromo-6-chloro-2-fluoroaniline features a trihalogenated aromatic core with strategic electronic tuning from the fluorine, chlorine, and bromine substituents. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a high-performance building block for pharmaceutical intermediates and functional materials.
3-Bromo-6-chloro-2-fluoroaniline serves as a versatile building block in the synthesis of functionalized aromatic scaffolds, particularly for pharmaceutical and agrochemical intermediates. Its orthogonal halogenation pattern enables selective cross-coupling reactions under palladium catalysis, facilitating efficient C–C and C–heteroatom bond formation. The molecule exhibits good bench stability and is compatible with common protecting group strategies, simplifying purification and downstream derivatization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: