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Structure of 942473-59-8
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2,5-Dibromo-isonicotinic acid features a pyridine ring bearing bromine substituents at the 2 and 5 positions, conferring enhanced electrophilicity and stability. This configuration enables direct functionalization in cross-coupling reactions and facilitates integration into bioactive scaffolds requiring halogen-directed derivatization.
2,5-Dibromo-isonicotinic acid serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its ortho-dibromo substitution enables palladium-catalyzed cross-coupling reactions with high efficiency, while the carboxylic acid group facilitates direct derivatization or salt formation. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: