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Structure of 941585-25-7
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tert-Butyl 3-mercaptoazetidine-1-carboxylate features a strained azetidine ring bearing a reactive thiol group and a bench-stable tert-butyl carbamate protecting group. This combination enables direct incorporation into cysteine-targeted conjugation strategies, offering high chemoselectivity in bioconjugation and peptide modification workflows.
tert-Butyl 3-mercaptoazetidine-1-carboxylate serves as a versatile synthetic building block for the construction of azetidine-containing scaffolds in medicinal chemistry. The thiol functionality enables efficient conjugation via gold-catalyzed cyclization or palladium-mediated coupling, while the tert-butyl ester offers convenient protection and orthogonal deprotection under mild acidic conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate integration into complex molecule synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: