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CS-W001157 4
Total: USD 88.00

Benzyl 4-hydroxybenzoate

  • CAS No. 94-18-8

  • Cat. No. CS-W014198
  • Purity≥95%
  • MDL No.MFCD00016471

*For research and further manufacturing use only, not for direct human use.

Benzyl 4-hydroxybenzoate|CS-W014198

Structure of 94-18-8

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General Information

  • CAS No. 94-18-8
  • Cat. No. CS-W014198
  • Purity ≥95%
  • MDL No. MFCD00016471
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂O₃
  • Molecular Weight 228.25
  • Synonym(s) Benzyl Paraben
  • SMILES O=C(OCC1=CC=CC=C1)C2=CC=C(O)C=C2

Description

Benzyl 4-hydroxybenzoate (Paraben, Benzyl Paraben) is an ester of para-hydroxy benzoic acid. It has been added to various cosmetics and personal care products as a preservative. Its quantification in cosmetics has been reported by HPLC methods. Microwave assisted synthesis of benzyl 4-hydroxybenzoate by reaction between (4-hydroxybenzoic) acid and K2CO3 in presence of phase transfer catalyst has been reported. It is an endocrine disrupting chemical (EDC). It is a promising candidate for use in pharmaceutical and personal care products. Its visible-light assisted photosensitized degradation in homogeneous aqueous solution of 4,4,4,4-(porphine-5,10,15,20-tetrayl)tetrakis(benzenesulphonic acid) has been investigated.Benzyl 4-hydroxybenzoate may be used as internal standard for the simultaneous analysis of non-steroidal anti-inflammatory drugs in human plasma and urine using microextraction by packed sorbent and HPLC method. It may be employed as internal standard for the HPLC determination of rutin, kaempferol, genistein, formononetin and biochanin A in Ononis spinosu roots.

Synthesis

  • Route1
    • null|null
      100-39-0
    • 4-Hydroxybenzoic acid  Cetirizine Impurity|CS-0167040
      99-96-7
    • ~92%
    • In-stock
      Benzyl 4-hydroxybenzoate|CS-W014198
      94-18-8

    References

    • Guo, Wei; Li, Junfei; Fan, Ningjuan; Wu, Weiwei; Zhou, Peiwen; Xia, Chizhong Synthetic Communications, 2005 , vol. 35, # 1 p. 145 - 152
  • Route2
    • null|null
      100-39-0
    • In-stock
      4-Hydroxybenzoate sodium|CS-W010880
      114-63-6
    • ~84%
    • In-stock
      Benzyl 4-hydroxybenzoate|CS-W014198
      94-18-8

    References

    • Yang, Hung-Ming; Chu, Wei-Ming Ultrasonics Sonochemistry, 2014 , vol. 21, # 1 p. 395 - 400
  • Route3
    • null|null
      24285-46-9
    • ~99%
    • In-stock
      Benzyl 4-hydroxybenzoate|CS-W014198
      94-18-8

    References

    • Gomez-Vidal; Forrester; Silverman Organic letters, 2001 , vol. 3, # 16 p. 2477 - 2479

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H401
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   2.7492
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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